Anycubic Kobra S1 Combo
- Speed
- 600 mm/s
- Score
- 8.2/10
- Wins
- 2/5
Anycubic Kobra S1 Combo vs Prusa MK4S
- The Anycubic Kobra S1 Combo wins, 8.2 vs 7.8 out of 10.
- Kobra S1 Combo prints 1.4× the volume (250×250×260 ÷ 250×210×220 = 1.41) and costs less.
- Kobra S1 Combo is faster, 600 vs 200 mm/s.
- Pick the Prusa MK4S if your prints fit in 22 cm.
Specs from the PrintPick catalog, checked 2026-09-29. Scores are PrintPick ratings out of 10.
Prusa MK4S
- Speed
- 200 mm/s
- Score
- 7.8/10
- Wins
- 2/5
The verdict
Buy the Kobra S1 Combo.
8.2/10 vs Prusa MK4S's 7.8/10, and it wins 2 of 5 categories. Best multi-color pick if you want more than 4 colors and can't justify going over $500. For figurines, cosplay parts, and detailed decorative prints, the jump from 4 to 8 colors matters more than the spec sheet suggests.
Specs, side by side
Teal wins the row.
Kobra S1 ComboAnycubic · FDM
vsPrusa MK4SPrusa Research · FDM
| Kobra S1 Combo | Spec | Prusa MK4S |
|---|---|---|
| 16.3 L (wins) | Build volume | 11.6 L |
| 600 mm/s (wins) | Top speed | 200 mm/s |
| 0.05 mm | Finest layer | 0.05 mm |
| 12.5 kg | Weight | 7 kg |
Features
| Kobra S1 Combo | Feature | Prusa MK4S |
|---|---|---|
| Yes | 8-color ACE Pro 2 multi-color system | No |
| Yes | CoreXY architecture | No |
| Yes | Auto bed leveling | Yes |
| Yes | WiFi + camera monitoring | No |
| Yes | Direct drive extruder | No |
| Yes | PEI spring steel build plate | No |
| No | Open source | Yes |
| No | PrusaSlicer | Yes |
| No | Nextruder | Yes |
| No | Input shaping | Yes |
| No | Ethernet | Yes |
Scores out of 10
| Kobra S1 Combo | Spec | Prusa MK4S |
|---|---|---|
| 8 (wins) | Value | 6 |
| 8 | Beginner Friendliness | 8 |
| 8 | Print Quality | 9 (wins) |
| 9 (wins) | Speed | 6 |
| 8 | Reliability | 10 (wins) |
| 8.2 (wins) | Overall | 7.8 |
Build space, front view, to one scale
- 250 × 250 × 260 mm
- 250 × 210 × 220 mm
What owners say
8 colors out of the box changes the game. My multi-color prints are finally as detailed as I imagined them.
Kobra S1 Combo owner, r/3DprintingThe ACE Pro 2 is a massive improvement. Less waste, more reliable color swaps, and double the colors.
Kobra S1 Combo owner, Teaching Tech (YouTube)Anycubic's answer to Bambu's multi-color dominance. Competitive on every front.
Kobra S1 Combo owner, All3DPMy MK3 ran for 5 years without a single failed print. The MK4S continues that legacy.
Prusa MK4S owner, r/prusa3dIf reliability is your #1 priority, nothing beats Prusa. Nothing.
Prusa MK4S owner, Thomas Sanladerer (YouTube)
Pros & Cons
Kobra S1 Combo
- +8 colors out of the box, double what the Bambu A1 Combo offers
- +CoreXY speed at a competitive price point
- +ACE Pro 2 wastes less filament on color swaps than its predecessor
- −Anycubic's software is solid but still behind Bambu Studio
- −Community is smaller than Bambu or Creality
Prusa MK4S
- +Prusa's QC is genuinely better than anyone else's: every printer is test-printed before shipping
- +PrusaSlicer is open source and powerful, no subscription, no cloud required
- +Customer support answers in hours, not weeks
- −200mm/s max is a third of what CoreXY machines do at half the price
- −The price for an open-frame bed-slinger is a hard sell in 2025
Buy these with it
A printer does nothing without these. Grab them in the same order.
- ELEGOO PLA filament, 1kgThe easy filament to start on. Prints at low temperatures and warps less.
- ELEGOO PETG filament, 1kgTougher and more heat tolerant than PLA, for parts that get handled or sit in the sun.
- SUNLU filament dryer S1 PlusWet filament causes stringing and rough surfaces. A dryer fixes that before you blame the printer.
Frequently Asked Questions
Is the Anycubic Kobra S1 Combo better than the Prusa MK4S?
By the numbers, the Anycubic Kobra S1 Combo scores higher (8.2/10). But "better" depends on your use case, the Prusa MK4S may be the smarter buy if you need reliability.
Which is better for beginners, Anycubic Kobra S1 Combo or Prusa MK4S?
Both score 8/10 for beginners. Go with the Anycubic Kobra S1 Combo, the cheaper of the two.
Is the Prusa MK4S worth paying more for over the Anycubic Kobra S1 Combo?
The Anycubic Kobra S1 Combo actually scores higher (8.2/10) despite costing less. The Prusa MK4S only makes sense if you specifically need reliability.
What's the main difference between Anycubic Kobra S1 Combo and Prusa MK4S?
Build volume (250x250x260mm vs 250x210x220mm) and print speed (600 vs 200 mm/s). The Anycubic Kobra S1 Combo is best for multi-color; the Prusa MK4S targets reliability.